Join Date: May 2019
Location: Minnesota, USA
Car Year & Model: 2018 GLA45
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I would guess, and just a guess, that it is possible for that to cause a repeatable misfire. Can't extrapolate as to exactly what the cause would be though. There are so many conditions and variables, it doesn't take much to cause a misfire.
On a related note, I was having the same issue. Multiple misfire codes, getting worse and worse. Replaced plugs, coils, fuel pump, etc. End up being water in the gas. And not very much water either. Just a trace amount in the sample drawn from the tank. That small amount of water was causing several mechanical components to rust if it sat for a couple days.
It was found by sending a borescope down the spark plug hole to inspect the cylinder walls after sitting for a few days. Rusty. Then tested the gas in the tank.
Drained the gas, refilled with fresh, and the problem has gone away. Might be worth a try?
Good luck, and let us know how it goes!
To hesitate is a waste of time.